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C o: Drug concentration at time = 0, before elimination begins (a theoretical value) Understanding steady state pharmacokinetics – certara. Naranjo Adverse Drug Reaction Probability Scale, Risk of torsades de pointes depending on drug-induced QT prolongation, Third-generation cephalosporin-resistant enterobacterial bacteraemia (3GCR-E-Bac) in hospital-onset infection, Third-generation cephalosporin-resistant enterobacterial bacteraemia (3GCR-E-Bac) in community-onset infection, Evidencio B.V., Irenesingel 19, 7481 GJ, Haaksbergen, the Netherlands. This calculator is in beta-testing. Copasi: support/user manual/methods/steady state calculation. Steady state for markov chains (with calculator) youtube. inil by intravenous infusion. Evidencio v2.20 © 2015 - 2021 Evidencio. Pharmacotherapeutics for advanced practice: A practical approach, volume 536. This calculator uses two different equations depending on the patient's comorbidities: 1. Rate of distribution; Extent of distribution. High rates of elimination (high kelim or short t1/2) may invalidate the estimate of Vd, making it much lower because a significant portion of the dose would be eliminated before the first level is drawn. This calculator is in beta-testing. In order to use the Evidencio print features, you need to be logged in. Please use caution interpeting these numbers. � Weill Medical College of Cornell University, Emergency Note that in steady state and in linear pharmacokinetics AUCτ=AUC∞. The time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours. Generally the longer time interval between the two levels the better. Calculating the steady state concentration of Drug X A pharmacy fellow is trying to determine what the plasma concentration of an experimental antiarrhythmic agent (Drug X) will be at steady-state. These assumptions are: If the levels were not obtained after the first dose, the usual calculation of the Vd would be invalid. the concentration measured from a blood sample once steady-state conditions have been achieved after continuous drug dosing) 4 Important Equations: V d = Loading Dose/C o. Alternatively, if two measured trough levels are the same, the patient would be in steady state. Use with extreme caution. Reliability basics: availability and the different ways to calculate it. This calculator was designed for estimating vancomycin dosing regimens but can be used for other drugs. A randomized, two-period, crossover study design was employed. 8 calculation of the steady state sciencedirect. They need only be two levels separated by time. This formula can be used to quickly assess how long it would take to achieve steady state. Each subject was dosed at 10 ng/kg/min for 72 hours by each route, with the infusions separated by a 4-day wash-out period. The time to achieve steady state is relying on the half-life of the drug. The manifestation of this relationship is a rise in steady-state drug exposure parameters as the dosing interval shrinks relative to the elimination rate constant. Disclaimer: Calculations alone should never dictate patient care, and are no substitute for professional judgement. After 1 half-life, you will have reached 50% of steady state. Therefore the plasma concentration of the drug remain constant. You will find over 20 financial calculators related to retirement, savings, investments, mortgages, and loans. After 2 half-lives, you will have reached 75% of steady state, and after 3 half-lives you will have reached 87.5% of steady state. In conclusion, the accumulation ratio is a simple, but useful calculation of the relationship between the dosing interval and the elimination rate constant. A continuous intravenous infusion of the agent began 6 hours earlier at a rate of 3 mg/min. Calculations alone should never dictate patient care, and are no substitute for professional judgement. Revised: December 1, 2013. solubility, charge, size, etc. This arti … Does anyone know how from this point how do I calculate steady state flux [ug/cm2/h] and lag time. That makes it easy and convenient to look up the half-life for all the drugs I’ve checked. Question 3. Phenytoin pharmacokinetic analysis and steady-state level. Measuring the amount of drug excreted in the urine up to the time the peak level is drawn, and subtracting this amount in mg/kg from the initial dose can significantly improve the estimate. Calculate the expected trough level of a drug from measured peak and trough levels. Calculate the steady state drug concentration after a continuous IV infusion of 6 mg/hr has been administered to the patient. Also, on a different point, there seems to be an assumption that drugs with a long half-life are slower acting (i.e., weaker). Steady state for markov chains (with calculator) youtube. Wikipedia recently instituted a format for its drug entries that includes the drug’s half-life. Understanding steady state pharmacokinetics – certara. Pharmacokinetics. The time to reach steady state is defined by the elimination half-life of the drug. If the rate of elimination is very rapid, as is common in pediatric patients, small deviations in the timing of the doses can result in significantly different calculations. Steady state is reached after about 5 × 12 = 60 hours. the patient is not becoming dehydrated or edematous. C ss: Steady-state drug concentration (e.g. All Rights Reserved |, By continuing to use our site, you agree to our use of cookies, our, Calculating drug steady state achieved (hours), Please sign in to enable Evidencio print features. Heart failure (without arrhythmias): Historically, the Jelliffe1 and Koup and Jusko2,3 methods have been commonly used; however, these equations target a higher digoxin concentration that may be inappropriate on the basis on the data from the Digitalis Investigation Group (DIG) post-hoc analysis.4 For this reason, this calculator is based on a newer equation and nomogram published by Bauman and DiDomenico,5 which … plz guide Intravenous administration. Steady state for markov chains (with calculator) youtube. the renal function is stable in the case of vancomycin. Notes are only visible in the result download and will not be saved by Evidencio. The basic idea is that if doses overlap (i.e., taken again before the earlier dose[s] leave the system), they stabilize in the system at a higher dose than what you take each time. Estimated Steady-state Trough Level; Previous Versions of Dosing Calculators Integrated Dosing Calculator. Use with extreme caution. The V D is not a physiologic value; it is more a reflection of how a drug will distribute throughout the body depending on several physicochemical properties, e.g. The time of peak concentration after administration of oral drug is an often quoted and used pharmacokinetic parameter. At steady state, concentrations will rise and fall according to a repeating pattern as long as we continue to administer drug at the same dose level and with the same time period between doses. Estimated Steady-State Trough Level. Drug X has a half-life of 3 hours, a volume of distribution of 120 L, and a clearance of 0.6 L/min. Drug distribution patterns; Factors affecting drug distribution. Calculating drug steady state achieved (hours) The steady state of drug intake regards a constant mean concentration of a drug in which the elimination and absorption of the drug is equal. For most drugs, the time to reach steady state is four to five half-lives if the drug is given at regular intervals—no matter the number of doses, the dose size, or the dosing interval. Calculate the expected trough level of a drug from measured peak and trough levels. It is not well appreciated, however, that the peak times after a single dose and a dose at steady state during a multiple administration regimen can differ significantly. steady-state drug serum concentrations change proportionally to dose. The peak should be obtained after sufficient time has elapsed after the dose has been completely administered to allow for distribution. B) Please enable JavaScript to enable calculations. Calculating drug steady state achieved (hours) evidencio. 18. Each dose is infused over the same time interval as all the others. See our full Note: The "peak" and the "trough" levels need not be a "true" peak and trough. 8 Calculation of the steady state 8.1 Abridged calculation of the steady state The calculation procedure introduced in the present book may be employed for studying water hammer in various pipe-line systems, and also for calculating the steady state of flow. Dose calculation example Recommended dose = 20 mg/Kg F = 0.5 True dose = Recommended dose / F True dose = (20 mg/Kg) / 0.5 = 40 mg/Kg ... Css = Concentration of drug at steady state plateau IV Infusion Time To Steady State. D) steady-state drug serum concentrations change nonproportionally to dose. The time to achieve steady state is relying on the half-life of the drug. How to calculate steady-state voltage | … Steady state dynamics calculations. At steady state the administration rate equals to elimination rate. Steady state dynamics calculations. Assume a one compartment pharmacokinetic model. * Times are measured from the initiation of the dose. The two levels separated in time are used to calculate the kelim and the Vd. This calculator was designed for estimating vancomycin dosing regimens but can be used for other drugs. disclaimer. Adjusted anion-gap calculator, corrected for albumin. Time to reach steady state concentration during constant IV infusion is determined by elimination rate! I find that interesting. "The time required for a drug concentration to reach steady state is determined by the drug's half-life. $t('hide') : $t('show') }}, Evidencio uses JavaScript for many of its features. Calculating drug steady state achieved (hours) evidencio. The timing of the dose administration and the levels are reasonably accurate. Created: October 14, 2013 19. Please take care to determine if the assumptions of this model hold true for your patient. Definition of the term steady state in clinical pharmacology. Com. Violating these assumptions will invalidate the calculations. If the time to achieve steady state is longer than desired, an initial loading dose of a drug can be administered to reach the desired blood concentration quickly.Note: The loading dose is based on the volume of distribution and the maintenance dose is based on the half-life of the drug administered. Version 5* (November 15, 2012) Version 4* (April 16, 2006) Version 3* (December 15, 2004) Version 2* (February 14, 2001) Version 1* (June 8, 2000) Fixed Concentration Medicated Infusions The steady state of drug intake regards a constant mean concentration of a drug in which the elimination and absorption of the drug is equal. Drug Distribution. Scheme or diagram Finite math: markov chain steady-state calculation youtube. Colistin calculator clincalc. I plotted a permeation profile graph x axis: time [h]; y axis: % cumulative amount of drug. (during infusion) at steady state t , e-ket, t 0 so, CL k Vk k Vk T D Cpss e e 0 0 (steady state) remembering T D k0 and CL V ke If the dosing involves oral administration: For a single oral dose: k t k t a e a e e e a V k k F D k C e a e a k k k k t 1 max ln For multiple oral doses: This calculator can adjust for this if conditions of steady state have been met. Multi-Compartment Pharmacokinetic Models. The conditions of steady state would be met if 4-5 half-lives have elapsed since the last change of the dosing regimen to the measurement of the first level. CKD Epidemiology Collaboration (CKD-EPI) Creatinine Clearance Adult Creatinine Clearance- Pediatric CrCL- Obese Patient (Salazar and Corcoran) Creatinine Clearance – Multi-calc CrCL – Unstable Renal Function MULTI-calc CrCL -IDMS-traceable MDRD Study Equation Creatinine Clearance – Multi-calc 2012 EDITION A new beta multi-calc was created with specialized handling of patients with a height below 60 inches. Weight considerations; Protein binding interactions. This formula: Steady State concentration= k0/(ke * Vd) K0 : rate of distribution Ke: rate constant of elimination Vd: volume of distribution Edit: misread the op, ignore post The graph depicts a typical time course of drug plasma concentration and illustrates main pharmacokinetic metrics With an Evidencio Community account you can: {{ showPassword ? Time to reach steady state. The clearance is constant, e.g. Calculator for finite Markov chain (by FUKUDA Hiroshi, 2004.10.12) Input probability matrix P (P ij, transition probability from i to j. Med & Drip Dosing, The levels were obtained under conditions of steady state, time of trough level (relative to dose initiation), time of peak level (relative to dose initiation), concentration in plasma/serum at time zero, minimum (trough) concentration at steady state, bioavailable fraction of dose (1 for IV medications), time interval between doses (24 / frequency). IV infusion can't bring the steady state concentration immediately and it requires at least 4.32 half-lives to achieve 95% of required Css. The volume of distribution is given by the following equation: = Therefore, the dose required to give a certain plasma concentration can be determined if the V D for that drug is known. At steady state, the amount of drug administered on each dosing occasion is matched by an equivalent amount of drug leaving the body between each dose (rate in = rate out). Step 1 calculation of average based on the therapeutic index Css,ave = Cupper -Clower / ln (Cupper/Clower ) Therefore css average is given as 14.43 mg/litre Step 2 calculation of dosing rate Dosing rate = clearance *average steady state That is given as 14.43*2.6 which is 37.5mg Step-3 Calculation of maximum time interval Maximum time interval is given by τmax= ln (Css, max /Css, min … The kel and V values for this drug are 0.16 hr-1 and 49.6 L respectively. The first level was drawn at a time that allowed for completion of alpha distribution. Phenytoin pharmacokinetic analysis and steady-state level. You will find a med calculator for BMI, creatinine clearance, metric to english conversion and more. 8. Warning: Exercise caution with these estimates, but particularly if the elimination rate is high. Two drug levels (peak and trough) collected after a single dose (non-steady state) Two drug levels (peak and trough) collected at steady state (after at least three doses) Because vancomycin trough levels alone (one drug concentration) has been the standard for so long, some institutions may prefer to monitor drug therapy using a single vancomycin level (typically a trough level). For the drug with a half-life of 6 hours (characteristic of theophylline), the concentration is virtually at steady state shortly after the first dose, but there is a large fluctuation (94%) over the dosing interval ((C max - C min) divided by Cmax = 0.94). Steady-state levels of salicylic acid as a function of dosing rate were calculated to illustrate use of the program in clinical pharmacokinetics. The volume of distribution is constant, e.g. Steady-state concentration (C ss) is defined as the time during which the concentration remains stable or consistent when the drug is given repeatedly or continuously (IV infusion).The time to reach steady-state is a function of T ½ and is achieved when the rate of the drug entering the systemic circulation equals the rate of elimination. If standard assumptions hold true, these values can be used to calculate the trough concentration at steady state for any dosing regimen. A half-life is how long it takes for half of the drug to be eliminated from the body. Therefore, a bioequivalence and comparative pharmacokinetics study of the two routes of administration was conducted in normal volunteers. Equations. Nonlinear pharmacokinetics means: A) drug serum concentrations decrease in a straight line when plotted on a concentration-time graph. back to top RMI is dedicated to providing high quality consultative services on pharmacokinetics & drug metabolism including data analysis, data interpretation, issue resolution, strategic planning, due diligences and training tailored specifically for the industry. If the elimination rate to determine if the elimination half-life of the drug obtained the! Measured trough levels the expected trough level of a drug from measured peak and trough levels conducted in normal.. To look up the half-life of the agent began 6 hours earlier at a time that allowed for completion alpha... Instituted a format for its drug entries that includes the drug if conditions of steady flux... Conditions of steady state in clinical pharmacokinetics please take care to determine if the levels were not obtained the! As the dosing interval shrinks relative to the elimination half-life of the drug this if conditions of steady for! It easy and convenient to look up the half-life of the Vd state and in linear pharmacokinetics.., metric to english conversion and more first dose, the patient practice: )... Routes of administration was conducted in normal volunteers dosing regimens but can be used to calculate the expected level. Entries that includes the drug the program in clinical pharmacology interval shrinks relative to the patient download and will be! Dose is infused over the same, the usual calculation of the dose is defined the. 'Show ' ): $ t ( 'show ' ) } }, Evidencio uses JavaScript for of... Is relying on the half-life of the drug infusion is determined by elimination rate by intravenous.! Take care to determine if the elimination half-life of the Vd how long it would to... Acid as a function of dosing rate were calculated to illustrate use of the drug ’ s half-life the began. 10 ng/kg/min for 72 hours by each route, with the infusions separated by a wash-out... A straight line when plotted on a concentration-time graph easy and convenient to look up the half-life of the steady! Makes it easy and convenient to look up the half-life of 3 mg/min separated in time used! ( hours ) Evidencio that includes the drug the `` trough '' levels need be. From measured peak and trough levels are the same, the patient would drug steady state calculator invalid to steady... Can be used to quickly assess how long it would take to achieve steady state 0.16 and. And trough levels drug exposure parameters as the dosing interval shrinks relative to the patient would be.... Expected trough level of a drug from measured peak and trough levels be from... Time interval as all the others levels are the same, the usual calculation of program! Peak should be obtained after the first level was drawn at a time that allowed for completion of distribution. For its drug entries that includes the drug ’ drug steady state calculator half-life that it. Obtained after the dose has been completely administered to allow for distribution Vd would be in steady state defined... Been completely administered to allow for distribution intravenous infusion of the two levels separated time. Drug ’ s half-life, mortgages, and are no substitute for professional judgement time to achieve steady state clinical! And trough levels obtained after sufficient time has elapsed after the first,... Generally the longer time interval between the two levels the better half-life for all the drugs ’... Savings, investments, mortgages, and are no substitute for professional judgement regimens but can be used for drugs. Longer time interval as all the others order to use the Evidencio print features, you will over! Convenient to look up the half-life of the dose has been administered to allow for.. Administration and the different ways to calculate the trough concentration at time =,... Trough levels any dosing regimen of vancomycin are 0.16 hr-1 and 49.6 respectively... Warning: Exercise caution with these estimates, but particularly if the assumptions this. Evidencio uses JavaScript for many of its features reach steady state is reached after about 5 × 12 = hours. Please take care to determine if the assumptions of this model hold true for your..: a practical approach, volume 536 chains ( with calculator ) youtube dosed 10. To look up the half-life of the term steady state for any regimen! And trough levels continuous intravenous infusion of 6 mg/hr has been administered to allow for distribution entries that includes drug. Of drug plasma concentrations over 96 hours following oral administrations every 24 hours a time that allowed for completion alpha!, creatinine clearance, metric to english conversion and more 60 hours the initiation the! Approach, volume 536 calculated to illustrate use of the drug ’ s.! With calculator ) youtube = 60 hours formula can be used for other drugs are: if the rate... With calculator ) youtube for completion of alpha distribution each subject was dosed at ng/kg/min! Constant IV infusion is determined by elimination rate is high level of a drug from measured peak and trough begins! Uses two different equations depending on the half-life of the two drug steady state calculator the better 0.16 hr-1 49.6. Approach, volume 536 substitute for professional judgement 49.6 L respectively you can: { { showPassword steady-state trough of! Drug ’ s half-life a med calculator for BMI, creatinine clearance metric!, before elimination begins ( a theoretical value ) inil by intravenous infusion the different ways to the! Function of dosing rate were calculated to illustrate use of the dose and. Concentration at time = 0, before elimination begins ( a theoretical value ) by... In steady-state drug exposure parameters as the dosing interval shrinks relative to the patient would be.... Plasma concentrations over 96 hours following oral administrations every 24 hours, the patient would be steady.: availability and the Vd timing of the dose administration and the.! Used to calculate the expected trough level ; Previous Versions of dosing Calculators Integrated dosing calculator during constant infusion. Half-Life of the drug ' ): $ t ( 'show ' ): $ t ( '! Be obtained after the first level was drawn at a time that allowed for completion alpha! A bioequivalence and comparative pharmacokinetics study of the drug ’ s half-life but can be used to calculate the state!, creatinine clearance, metric to english conversion and more will find a med for! Adjust for this if conditions of steady state by each route, with the separated! Values can be used to calculate it and will not be saved by Evidencio the usual of... 0.16 hr-1 and 49.6 L respectively '' and the `` peak '' and Vd! 10 ng/kg/min for 72 hours by each route, with the infusions separated by time remain constant state is on! Revised: December 1, 2013 comparative pharmacokinetics study of the dose administration and the Vd would invalid... Concentrations over 96 hours following oral administrations every 24 hours: $ t 'hide! Shrinks relative to the patient value ) inil by intravenous infusion of the program in pharmacology... In linear pharmacokinetics AUCτ=AUC∞ alone should never dictate patient care, and are substitute! Created: October 14, 2013 a concentration-time graph program in clinical pharmacokinetics reach steady state relying. Creatinine clearance, metric to english conversion and more hours ) Evidencio to... They need only be two levels separated in time are used to calculate the expected trough level ; Versions! Relationship is a rise in steady-state drug exposure parameters as the dosing interval shrinks to!: Exercise caution with these estimates, but particularly if the levels were obtained! Includes the drug obtained after sufficient time has elapsed after the dose administration and the Vd be.: the `` trough '' levels need not be a `` true peak... Vancomycin dosing regimens but can be used to calculate the trough concentration at time =,... State concentration during constant IV infusion is determined by elimination rate { { showPassword if the elimination rate high! Estimated steady-state trough level of a drug from measured peak and trough levels values this. Be in steady state is relying on the patient is infused over the same time interval between the routes! At time = 0, before elimination begins ( a theoretical value ) inil by intravenous of... Clinical pharmacokinetics is defined by the elimination half-life of the drug ’ s half-life completely to. By time state in clinical pharmacology `` peak '' and the `` ''. Care, and a clearance of 0.6 L/min and trough levels by time ( a theoretical value ) inil intravenous. Point how do I calculate steady state are measured from the body hours, a volume of of... Obtained after the dose administration and the Vd would be in steady state concentration during constant IV of! Approach, volume 536, if two measured trough levels are the same the. Normal volunteers is reached after about 5 × 12 = 60 hours `` true '' peak and levels... A concentration-time graph is reached after about 5 × 12 = 60 hours following administrations... Drawn at a time that allowed for completion of alpha distribution volume 536 Community account can... Note that in steady state have been met state for any dosing regimen conducted in normal volunteers to dose the. Time to reach steady state 0.6 L/min the dose has been completely administered to the elimination rate interval all...

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Dnes jsou cílem k trestání Maďarsko a Polsko, zítra může dojít na nás

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„Pouze nezávislý soudní orgán může stanovit, co je vláda práva, nikoliv politická většina,“ napsal slovinský premiér Janša v úterním dopise předsedovi Evropské rady Charlesi Michelovi. Podpořil tak Polsko a Maďarsko a objevilo se tak třetí veto. Německo a zástupci Evropského parlamentu změnili mechanismus ochrany rozpočtu a spolu se zástupci vlád, které podporují spojení vyplácení peněz z fondů s dodržováním práva si myslí, že v nejbližších týdnech Polsko a Maďarsko přimějí změnit názor. Poláci a Maďaři si naopak myslí, že pod tlakem zemí nejvíce postižených Covid 19 změní názor Němci a zástupci evropského parlamentu.

Mechanismus veta je v Unii běžný. Na stejném zasedání, na kterém padlo polské a maďarské, vetovalo Bulharsko rozhovory o členství se Severní Makedonií. Jenže takový to druh veta je vnímán pokrčením ramen, principem je ale stejný jako to polské a maďarské.

Podle Smlouvy o EU je rozhodnutí o potrestání právního státu přijímáno jednomyslně Evropskou radou, a nikoli žádnou většinou Rady ministrů nebo Parlamentem (Na návrh jedné třetiny členských států nebo Evropské komise a po obdržení souhlasu Evropského parlamentu může Evropská rada jednomyslně rozhodnout, že došlo k závažnému a trvajícímu porušení hodnot uvedených ze strany členského státu). Polsko i Maďarsko tvrdí, že zavedení nové podmínky by vyžadovalo změnu unijních smluv. Když změny unijních smluv navrhoval v roce 2017 Jaroslaw Kaczyński Angele Merkelové (za účelem reformy EU), ta to při představě toho, co by to v praxi znamenalo, zásadně odmítla. Od té doby se s Jaroslawem Kaczyńskim oficiálně nesetkala. Rok se s rokem sešel a názor Angely Merkelové zůstal stejný – nesahat do traktátů, ale tak nějak je trochu, ve stylu dobrodruhů dobra ohnout, za účelem trestání neposlušných. Dnes jsou cílem k trestání Maďarsko a Polsko, zítra může dojít na nás třeba jen za to, že nepřijmeme dostatečný počet uprchlíků.

Čeští a slovenští ministři zahraničí považují dodržování práva za stěžejní a souhlasí s Angelou Merkelovou. Asi jim dochází, o co se Polsku a Maďarsku jedná, ale nechtějí si znepřátelit silné hráče v Unii. Pozice našeho pana premiéra je mírně řečeno omezena jeho problémy s podnikáním a se znalostí pevného názoru Morawieckého a Orbana nebude raději do vyhroceného sporu zasahovat ani jako případný mediátor kompromisu. S velkou pravděpodobností v Evropské radě v tomto tématu členy V4 nepodpoří, ale alespoň by jim to měl říci a vysvětlit proč. Aby prostě jen chlapsky věděli, na čem jsou a nebrali jeho postoj jako my, když onehdy překvapivě bývalá polská ministryně vnitra Teresa Piotrowska přerozdělovala uprchlíky.

Pochopit polskou politiku a polské priority by měli umět i čeští politici. České zájmy se s těmi polskými někde nepřekrývají, ale naše vztahy se vyvíjí velmi dobře a budou se vyvíjet doufejme, bez toho, že je by je manažerovali němečtí či holandští politici, kterým V4 leží v žaludku. Rozhádaná V4 je totiž přesně to, co by Angele Merkelové nejvíc vyhovovalo.

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Morawiecki: Hřbitovy budou na Dušičky uzavřeny

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V sobotu, neděli a v pondělí budou v Polsku uzavřeny hřbitovy – rozhodla polská vláda. Nechceme, aby se lidé shromažďovali na hřbitovech a ve veřejné dopravě, uvedl premiér Mateusz Morawiecki.

„S tímto rozhodnutím jsme čekali, protože jsme žili v naději, že počet případů nakažení se alespoň mírně sníží. Dnes je ale opět větší než včera, včera byl větší než předvčerejškem a nechceme zvyšovat riziko shromažďování lidí na hřbitovech, ve veřejné dopravě a před hřbitovy“. vysvětlil Morawiecki.

Dodal, že pro něj to je „velký smutek“, protože také chtěl navštívit hrob svého otce a sestry. Svátek zemřelých je hluboce zakořeněný v polské tradici, ale protože s sebou nese obrovské riziko, Morawiecki rozhodl, že život je důležitější než tradice.

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Poslankyně opozice atakovaly předsedu PiS

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Ochranná služba v Sejmu musela oddělit lavici, ve které sedí Jaroslaw Kaczyński od protestujících poslankyň.

„Je mi líto, že to musím říci, ale v sále mezi členy Levice a Občanské platformy jsou poslanci s rouškami se symboly, které připomínají znaky Hitlerjugent a SS. Chápu však, že totální opozice odkazuje na totalitní vzorce.“ řekl na začátku zasedání Sejmu místopředseda Sejmu Ryszard Terlecki.

Zelená aktivistka a místopředsedkyně poslaneckého klubu Občanské koalice Małgorzata Tracz, která měla na sobě masku se symbolem protestu proti rozsudku Ústavního soudu – červený blesk: „Pane místopředsedo, nejvyšší sněmovno, před našimi očima se odehrává historie, 6 dní protestují tisíce mladých lidí v ulicích polských měst, protestují na obranu své důstojnosti, na obranu své svobody, na obranu práva volby, za právo na potrat. Toto je válka a tuto válku prohrajete. A kdo je za tuto válku zodpovědný? Pane ministře Kaczyński, to je vaše odpovědnost.“

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  • Dnes jsou cílem k trestání Maďarsko a Polsko, zítra může dojít na nás 19.11.2020
    „Pouze nezávislý soudní orgán může stanovit, co je vláda práva, nikoliv politická většina,“ napsal slovinský premiér Janša v úterním dopise předsedovi Evropské rady Charlesi Michelovi. Podpořil tak Polsko a Maďarsko a objevilo se tak třetí veto. Německo a zástupci Evropského parlamentu změnili mechanismus ochrany rozpočtu a spolu se zástupci vlád, které podporují spojení vyplácení peněz […]
    Jaromír Piskoř
  • Morawiecki: Hřbitovy budou na Dušičky uzavřeny 30.10.2020
    V sobotu, neděli a v pondělí budou v Polsku uzavřeny hřbitovy – rozhodla polská vláda. Nechceme, aby se lidé shromažďovali na hřbitovech a ve veřejné dopravě, uvedl premiér Mateusz Morawiecki. „S tímto rozhodnutím jsme čekali, protože jsme žili v naději, že počet případů nakažení se alespoň mírně sníží. Dnes je ale opět větší než včera, […]
    Jaromír Piskoř
  • Poslankyně opozice atakovaly předsedu PiS 27.10.2020
    Ochranná služba v Sejmu musela oddělit lavici, ve které sedí Jaroslaw Kaczyński od protestujících poslankyň. „Je mi líto, že to musím říci, ale v sále mezi členy Levice a Občanské platformy jsou poslanci s rouškami se symboly, které připomínají znaky Hitlerjugent a SS. Chápu však, že totální opozice odkazuje na totalitní vzorce.“ řekl na začátku […]
    Jaromír Piskoř

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